Recent trends in hepatitis B virus infection in the general Korean population
The Korean Journal of Internal Medicine
; : 413-419, 2013.
Article
Dans En
| WPRIM
| ID: wpr-212583
Responsable en Bibliothèque :
WPRO
ABSTRACT
BACKGROUND/AIMS:
Hepatitis B virus (HBV) is the major cause of chronic liver disease in Korea, but viral prevalence has decreased because of hepatitis B vaccination programs. In this study, we investigated longitudinal changes in HBV in fection in the general Korean population.METHODS:
HBV surface antigen (hepatitis B surface antigen, HBsAg) seropositivity was assessed from the Korea National Health and Nutrition Examination Survey (I to V). In total, 50,140 subjects were tested for serum HBsAg positivity over a period of 12 years (1998 to 2010).RESULTS:
The prevalence of HBsAg seropositivity decreased over the study period. The rates of HBsAg carriers were 4.61% in 1998, 4.60% in 2001, 3.69% in 2005, 3.01% in 2008, and 2.98% in 2010 (p 0.05). Neither gender nor socioeconomic status were associated with the decreased prevalence of HBsAg carriers.CONCLUSIONS:
HBV infection has decreased in the Korean population since the advent of vaccination programs. However, the decrease is limited to the younger population, and viral persistence remains in the middle-aged and older population.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Facteurs socioéconomiques
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Facteurs temps
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Marqueurs biologiques
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Loi du khi-deux
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Études séroépidémiologiques
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Prévalence
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Études transversales
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Enquêtes de santé
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Études longitudinales
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Facteurs âges
Type d'étude:
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limites du sujet:
Adolescent
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Adult
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Aged
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Child
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Female
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Humans
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Male
Pays comme sujet:
Asia
langue:
En
Texte intégral:
The Korean Journal of Internal Medicine
Année:
2013
Type:
Article