A Reverse Dipping Pattern Predicts Cardiovascular Mortality In a Clinical Cohort
Journal of Korean Medical Science
; : 1468-1473, 2013.
Article
de En
| WPRIM
| ID: wpr-212603
Bibliothèque responsable:
WPRO
ABSTRACT
An abnormal dipping pattern in ambulatory blood pressure monitoring (ABPM) is a cardiovascular (CV) risk factor. However, its impact on CV mortality has not been investigated sufficiently in clinical practice to be considered a standard parameter. We assessed the association between abnormal dipping patterns and increased CV mortality in a tertiary hospital in Korea. Our retrospective cohort study included 401 patients who underwent ABPM between 1994 and 1996 in Hanyang University Hospital, Seoul, Korea. The patients were classified as risers ( or =0% drop, n=294). The follow-up period was 120 months. The frequency of CV mortality was 14.0% in risers and 5.8% in others. A Cox regression analysis found a significant association between dipping pattern and CV mortality, after adjusting for age, gender, body mass index, hypertension, diabetes mellitus, smoking and hypercholesterolemia. Risers were at greater risk of CV death than others (RR, 3.02, P=0.022), but there was no difference in event rates between dippers and non-dippers. The reverse dipping pattern may be more frequent in clinical settings than in the population at large, and it is strongly associated with increased risk of CV mortality in Korea.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pression sanguine
/
Maladies cardiovasculaires
/
Indice de masse corporelle
/
Facteurs sexuels
/
Valeur prédictive des tests
/
Analyse de régression
/
Études rétrospectives
/
Facteurs de risque
/
Études de cohortes
/
Facteurs âges
Type d'étude:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Adult
/
Aged
/
Female
/
Humans
/
Male
langue:
En
Texte intégral:
Journal of Korean Medical Science
Année:
2013
Type:
Article