A Case of 5-fluorouracil-induced Phototoxicity / 대한피부과학회지
Korean Journal of Dermatology
; : 1364-1366, 2006.
Article
de Ko
| WPRIM
| ID: wpr-215676
Bibliothèque responsable:
WPRO
ABSTRACT
5-fluorouracil (5-FU) is an antimetabolite which prevents thymine synthesis and suppresses the utilization of preformed uracil. A variety of cutaneous reactions have been reported with the use of systemic 5-FU, the most common being photosensitivity. We report a case of 5-FU induced phototoxicity in a 73-year-old male. The patient had tender and slightly pruritic scaly and crusted erythema on sun-exposed areas. A biopsy revealed necrotic keratinocytes with epidermal degeneration. After the cessation of 5-FU, the skin lesions showed a marked improvement, and there was no further photosensitivity to the skin.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Peau
/
Thymine
/
Uracile
/
Biopsie
/
Kératinocytes
/
Dermatite phototoxique
/
Érythème
/
Fluorouracil
Limites du sujet:
Aged
/
Humans
/
Male
langue:
Ko
Texte intégral:
Korean Journal of Dermatology
Année:
2006
Type:
Article