Association between the Red Cell Distribution Width and Vasospastic Angina in Korean Patients
Yonsei med. j
; Yonsei med. j;: 614-620, 2016.
Article
de En
| WPRIM
| ID: wpr-21855
Bibliothèque responsable:
WPRO
ABSTRACT
PURPOSE: The association between the red cell distribution width (RDW) and vasospastic angina (VSA) has not been elucidated. We investigated the association of the RDW with the incidence and angiographic subtypes of VSA in Korean patients. MATERIALS AND METHODS: A total of 460 patients who underwent intracoronary ergonovine provocation tests were consecutively enrolled and classified into two groups: the VSA group (n=147, 32.0%) and non-VSA group (n=313, 68.0%). The subjects were classified into 3 subgroups (tertiles) according to the baseline level of RDW assessed before the angiographic provocation test. RESULTS: The VSA group had a higher RDW than the non-VSA group (12.9±0.8% vs. 12.5±0.7%, p=0.013). The high RDW level demonstrated an independent association with the high incidence of VSA [second tertile: hazard ratio (HR) 1.96 (1.13-2.83), third tertile: HR 2.33 (1.22-3.47), all p<0.001]. Moreover, the highest RDW tertile level had a significant association with the prevalence of the mixed-type coronary spasm [HR 1.29 (1.03-1.59), p=0.037]. CONCLUSION: The high level of RDW was significantly associated with the prevalence of VSA and the high-risk angiographic subtype of coronary spasm, suggesting that a proactive clinical investigation for VSA could be valuable in Korean patients with an elevated RDW.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Modèles des risques proportionnels
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Incidence
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Prévalence
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Coronarographie
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Spasme coronaire
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Index érythrocytaires
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République de Corée
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Angine de poitrine
Type d'étude:
Incidence_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limites du sujet:
Aged
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Aged80
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Female
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Humans
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Male
Pays comme sujet:
Asia
langue:
En
Texte intégral:
Yonsei med. j
Année:
2016
Type:
Article