Association study between age-related macular degeneration and R1210C mutation of CFH gene in Chinese population / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 570-572, 2012.
Article
de Zh
| WPRIM
| ID: wpr-232254
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>A R1210C mutation of complement factor H (CFH) gene has been associated with age-related macular degeneration (AMD) in Caucasian population. This study was to verify above association in Han Chinese population.</p><p><b>METHODS</b>The mutation was detected by direct sequencing in 258 patients with wet AMD and 426 matched controls.</p><p><b>RESULTS</b>The R1210C mutation has not been identified in either sample.</p><p><b>CONCLUSION</b>The R1210C mutation in CFH gene is not associated with AMD in Han Chinese population.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Facteur H du complément
/
Génétique
/
Dégénérescence maculaire
/
Mutation
Type d'étude:
Prognostic_studies
Limites du sujet:
Aged
/
Aged80
/
Female
/
Humans
/
Male
langue:
Zh
Texte intégral:
Chinese Journal of Medical Genetics
Année:
2012
Type:
Article