Effect of compound duzhong jiangu granule on knee joint osteoarthritis: a report of 400 cases / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the clinical efficacy and adverse reaction of compound Duzhong Jiangu granule (CDJG) on knee joint osteoarthritis (KJO) of Gan-Shen deficiency with stasis in tendon and muscle syndrome.</p><p><b>METHODS</b>The randomized controlled method was adopted in this study, comparative study was conducted in 400 patients in the treated group treated with CDJG and 200 patients in the control group treated with Zhuanggu Guanjie pill (ZGP).</p><p><b>RESULTS</b>The total effective rate in the treated group was 92% and the curative-markedly effective rate was 47%, which were higher than those in the control group respectively. Moreover, CDJG showed superiority in improving symptoms and with shorter initiating time of action as compared with ZGP. However CDJG had the effect more favourable for patients of mild condition.</p><p><b>CONCLUSION</b>CDJG is a kind of effective and safe medicine for treatment of KJO.</p>