Endometrial microvessel density for assessing endometrial receptivity during the peri-implantation period / 南方医科大学学报
Journal of Southern Medical University
; (12): 1365-1368, 2011.
Article
de Zh
| WPRIM
| ID: wpr-235122
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the value of endometrial microvessel density (MVD) in assessing the endometrial receptivity during the peri-implantation period.</p><p><b>METHODS</b>A total of 104 patients undergoing in vitro fertilization and embryo transfer (IVF-ET) treatment were analyzed retrospectively. The subjects were divided into clinical pregnancy group (50 cases) and nonpregnant group (54 cases) according to the IVF-ET outcome. Endometrial tissues were collected 7 days after the natural ovulation prior to IVF-ET for measurement of the endometrial MVD using electron microscopy, which was analyzed in relation to the clinical outcome of the treatment.</p><p><b>RESULTS</b>The endometrial MVD was significantly higher in the clinical pregnancy group than in the nonpregnant group [(4.12∓1.84)% vs (3.46∓1.26)%, t=-2.127, P=0.036). ROC curve analysis showed that the MVD had an area under the curve slightly over 0.5 (0.598) for predicting clinical pregnancy, suggesting a poor specificity in predicting the clinical outcome of the treatment.</p><p><b>CONCLUSION</b>In IVF-ET cycles, the endometrial MVD during the peri-implantation period is helpful for assessing the endometrial receptivity, but the specificity remains low.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Implantation embryonnaire
/
Physiologie
/
Thérapeutique
/
Imagerie diagnostique
/
Fécondation in vitro
/
Études rétrospectives
/
Échographie
/
Transfert d'embryon
/
Endomètre
/
Microvaisseaux
Type d'étude:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limites du sujet:
Adult
/
Female
/
Humans
langue:
Zh
Texte intégral:
Journal of Southern Medical University
Année:
2011
Type:
Article