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MicroRNA and left ventricular hypertrophy / 中国中药杂志
Zhongguo Zhong Yao Za Zhi ; (24): 3211-3215, 2014.
Article de Zh | WPRIM | ID: wpr-244593
Bibliothèque responsable: WPRO
ABSTRACT
MicroRNAs (miRNA) plays an important role in biological development and disease occurrence and development, and acts as a "main switch" in biology. Among patients of essential hypertension, around 1/3 would suffer left ventricular hypertrophy (LVH). Hence, essential hypertension becomes an independent risk factor for cardiovascular diseases. And miRNAs plays an important role in the occurrence and development of LVH. This paper reviewed the role of miRNA in regulating the stress signaling pathway, defined its impact on the occurrence of LVH, and further emphasized the opportunities and challenges of miRNA as a biomarker and therapeutic target.
Sujet(s)
Texte intégral: 1 Indice: WPRIM Sujet Principal: Transduction du signal / Facteurs de risque / Hypertrophie ventriculaire gauche / MicroARN / Hypertension essentielle / Génétique / Hypertension artérielle Type d'étude: Etiology_studies / Risk_factors_studies Limites du sujet: Humans langue: Zh Texte intégral: Zhongguo Zhong Yao Za Zhi Année: 2014 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Transduction du signal / Facteurs de risque / Hypertrophie ventriculaire gauche / MicroARN / Hypertension essentielle / Génétique / Hypertension artérielle Type d'étude: Etiology_studies / Risk_factors_studies Limites du sujet: Humans langue: Zh Texte intégral: Zhongguo Zhong Yao Za Zhi Année: 2014 Type: Article