Research Progress on Application of CRISPR/Cas Genome Editing Technology in Hematological Diseases -Review / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1284-1288, 2016.
Article
de Zh
| WPRIM
| ID: wpr-246774
Bibliothèque responsable:
WPRO
ABSTRACT
CRISPR/Cas genome editing technology is a newly developed powerful tool for genetic manipulation, which can be used to manipulate the genome at specific locations precisely, to restore the function of genetic defect cells, and to develop various disease models. In recentl years, with the advances of precise genome manipulation, CRISPR/Cas technology has been applied to many aspects of diseases research and becomes an unique tool to investigate gene function and discover new therapeutic targets for genetic diseases. Nowadays, CRISPR/Cas technology has been a hot research point in agriculture, graziery, biotechnology and medicine. This review focuses on the recent advances in CRISPR/Cas technology and its application in hematological diseases.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Phénotype
/
Techniques génétiques
/
Génome
/
Systèmes CRISPR-Cas
/
Édition de gène
/
Hémopathies
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
Journal of Experimental Hematology
Année:
2016
Type:
Article