The Recurrence of Seizure due to Decreased Valproic Acid Level after Administration of Carbapenem / 대한간질학회지
Journal of Korean Epilepsy Society
; : 64-66, 2007.
Article
de Ko
| WPRIM
| ID: wpr-25214
Bibliothèque responsable:
WPRO
ABSTRACT
Valproic acid (VPA) is one of the most commonly used antiepileptic drug, but has many drug-drug interactions. A 58-year-old male under the vegetative state has been well controlled with valproic acid (VPA) monotherapy without seizure attacks during the last 6 months. Pneumonia developed and panipenem-betamipron (PAPM-BP) for acinetobacter baumannii was administered. Seizure attacks recurred after 12 days of initiating PAPM-BP. During the maintenance period of PAPM-BP, serum level of VPA was decreased. After the cessation of PAPM-BP, serum level of VPA increased to the previous level without further seizure attacks. PAPM-BP should be cautiously used together with VPA because of possible drug-drug interaction.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pneumopathie infectieuse
/
Récidive
/
Crises épileptiques
/
Acide valproïque
/
État végétatif persistant
/
Acinetobacter baumannii
Limites du sujet:
Humans
/
Male
langue:
Ko
Texte intégral:
Journal of Korean Epilepsy Society
Année:
2007
Type:
Article