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The Recurrence of Seizure due to Decreased Valproic Acid Level after Administration of Carbapenem / 대한간질학회지
Article de Ko | WPRIM | ID: wpr-25214
Bibliothèque responsable: WPRO
ABSTRACT
Valproic acid (VPA) is one of the most commonly used antiepileptic drug, but has many drug-drug interactions. A 58-year-old male under the vegetative state has been well controlled with valproic acid (VPA) monotherapy without seizure attacks during the last 6 months. Pneumonia developed and panipenem-betamipron (PAPM-BP) for acinetobacter baumannii was administered. Seizure attacks recurred after 12 days of initiating PAPM-BP. During the maintenance period of PAPM-BP, serum level of VPA was decreased. After the cessation of PAPM-BP, serum level of VPA increased to the previous level without further seizure attacks. PAPM-BP should be cautiously used together with VPA because of possible drug-drug interaction.
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Texte intégral: 1 Indice: WPRIM Sujet Principal: Pneumopathie infectieuse / Récidive / Crises épileptiques / Acide valproïque / État végétatif persistant / Acinetobacter baumannii Limites du sujet: Humans / Male langue: Ko Texte intégral: Journal of Korean Epilepsy Society Année: 2007 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Pneumopathie infectieuse / Récidive / Crises épileptiques / Acide valproïque / État végétatif persistant / Acinetobacter baumannii Limites du sujet: Humans / Male langue: Ko Texte intégral: Journal of Korean Epilepsy Society Année: 2007 Type: Article