Progress in study of selective ERβ ligands / 药学学报
Acta Pharmaceutica Sinica
; (12): 658-667, 2015.
Article
Dans Zh
| WPRIM
| ID: wpr-257086
Responsable en Bibliothèque :
WPRO
ABSTRACT
Estrogen receptors (ERs) are members of nuclear receptors and related to several diseases such as cancer, inflammation and osteoporosis. ERs have two forms, ERα and ERβ, which have different functions and organism distributions. Compounds selectively targeting ERβ can regulate important physiological functions and avoid the side effects caused by targeting ERα. Therefore, selective ERβ ligands have received considerable research interest in recent years. In this article, different kinds of selective ERβ ligands were summarized and their structure-activity relationships were also analyzed.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Relation structure-activité
/
Chimie
/
Récepteur bêta des oestrogènes
/
Ligands
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
Acta Pharmaceutica Sinica
Année:
2015
Type:
Article