90d Exposure to Nonylphenol has Adverse Effects on the Spermatogenesis and Sperm Maturation of Adult Male Rats / 生物医学与环境科学（英文）
Biomedical and Environmental Sciences
; (12): 907-911, 2014.
Article
de En
| WPRIM
| ID: wpr-264637
Bibliothèque responsable:
WPRO
ABSTRACT
This study was conducted to elucidate the reproductive effect of NP on testis, epididymis and epididymal sperm in vivo. Adult male Sprague-Dawley rats were gavaged with NP at 0, 40, 100, or 250 mg/kg body weight (bw) on alternate days for 90 d. The results showed that oral administration of NP may damage the structure and function of testis, induce apoptosis and oxidative stress in epididymis or even have cytotoxic effects on epididymal sperm.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Anatomopathologie
/
Phénols
/
Mobilité des spermatozoïdes
/
Spermatogenèse
/
Spermatozoïdes
/
Testicule
/
Testostérone
/
Sang
/
Administration par voie orale
/
Rat Sprague-Dawley
Limites du sujet:
Animals
langue:
En
Texte intégral:
Biomedical and Environmental Sciences
Année:
2014
Type:
Article