Study of 17 immune cytokines in the peripheral blood of premature infants with chronic lung disease / 南方医科大学学报
Journal of Southern Medical University
; (12): 331-333, 2010.
Article
de Zh
| WPRIM
| ID: wpr-269558
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the immunomechanism of chronic lung disease (CLD) in premature infants by investigating the changes of 17 cytokines.</p><p><b>METHODS</b>Twenty-six preterm neonates who had been in the NICU for over 28 days were divided into CLD group (n=14) and control group consisting of 12 preterm neonates. Seventeen cytokines, namely interleukin 1b (IL-1b), IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12, IL-13, IL-17, granulocyte-macrophage colony-stimulating factor, interferon-gamma, tumour necrosis factor alpha, granulocyte colony-stimulating factor, monocyte chemoattractant protein 1, and macrophage inflammatory protein-1b were detected in a single sample of peripheral blood by multi-plex technology (Bio-plex).</p><p><b>RESULTS</b>There were no significant differences in the level of the 17 cytokines between the two groups (P>0.05).</p><p><b>CONCLUSION</b>The cytokines examined may not be involved in the later period pathogenesis of CLD.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Sang
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Prématuré
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Maladie chronique
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Cytokines
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Interleukines
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Interféron gamma
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Facteur de nécrose tumorale alpha
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Allergie et immunologie
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Maladies pulmonaires
Limites du sujet:
Female
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Humans
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Male
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Newborn
langue:
Zh
Texte intégral:
Journal of Southern Medical University
Année:
2010
Type:
Article