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Clinical application of magnetic resonance imaging in preoperative evaluation of endometrial cancer / 中国医学科学院学报
Zhongguo yi xue ke xue yuan xue bao ; Zhongguo yi xue ke xue yuan xue bao;(6): 455-460, 2012.
Article de En | WPRIM | ID: wpr-284350
Bibliothèque responsable: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the value of magnetic resonance imaging (MRI) in the preoperative assessment of endometrial cancer.</p><p><b>METHODS</b>Ninety-four patients with histopathologically confirmed endometrial carcinoma were retrospectively enrolled in this study. MRI findings were compared with the pathologic findings in all cases. The depth of myometrial invasion and lymph node metastasis were evaluated by T2 weighted imaging (T2WI) combined with contrast enhancement or diffusion weighted imaging (DWI).</p><p><b>RESULTS</b>Among these 94 patients,62 had no or superficial myometrial involvement and 32 cases had deep myometrial involvement. Meanwhile, 24 groups of metastatic lymph nodes and 164 groups of non-metastatic lymph nodes were detected. The accuracy, specificity, sensitivity, negative predictive value, and positive predictive value of T2WI combined with contrast enhancement in discriminating no/superficial myometrial involvement from deep myometrial involvement were 88.3%, 90.3%, 84.4%, 91.8%, and 81.8%, whereas those of T2WI combined with DWI were 81.9%, 87.1%, 71.9%, 85.7%, and 74.2%, respectively. The accuracy, specificity, sensitivity, negative predictive value, and positive predictive value of T2WI combined with contrast enhancement in identifying metastatic lymph nodes were 89.4%, 96.8%, 54.5%, 90.9%, and 78.3%, whereas those of T2WI combined with DWI were 91.5%, 95.5%, 72.7%, 94.3%, and 77.4%, respectively.</p><p><b>CONCLUSIONS</b>T2WI combined with contrast enhancement is superior to T2WI combined with DWI in evaluation of the depth of myometrial invasion. However, DWI is more sensitive in identifying lymph node metastasis than T2WI combined with contrast enhancement.</p>
Sujet(s)
Texte intégral: 1 Indice: WPRIM Sujet Principal: Anatomopathologie / Imagerie par résonance magnétique / Études rétrospectives / Sensibilité et spécificité / Tumeurs de l'endomètre / Diagnostic / Méthodes Type d'étude: Diagnostic_studies / Observational_studies / Prognostic_studies Limites du sujet: Adult / Aged / Female / Humans langue: En Texte intégral: Zhongguo yi xue ke xue yuan xue bao Année: 2012 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Anatomopathologie / Imagerie par résonance magnétique / Études rétrospectives / Sensibilité et spécificité / Tumeurs de l'endomètre / Diagnostic / Méthodes Type d'étude: Diagnostic_studies / Observational_studies / Prognostic_studies Limites du sujet: Adult / Aged / Female / Humans langue: En Texte intégral: Zhongguo yi xue ke xue yuan xue bao Année: 2012 Type: Article