Studies on the alkaloids from stem of Artabotrys hainanensis / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the alkaloids from the stem of Artabotrys hainanensis.</p><p><b>METHOD</b>Compounds in plant extracts were separated by silica gel and sephadex LH-20 column chromatography. Chemical structures were elucidated by chemical and spectral analyses including UV, 1H-NMR, 13C-NMR, ESIMS and ESI-MS-MS.</p><p><b>RESULT</b>Eight alkaloids were isolated and identified as spinosine (1), 3-hydroxynornuciferine (2), juzirine (3), artabotrine (4), liridine (5), assimilobine (6), isococlaurine (7), N-demethylarmepavine (8).</p><p><b>CONCLUSION</b>All alkaloids were isolated from this plant for the first time and compounds 1, 3, 7 and 8 were isolated from genus Artabotrys for the first time.</p>