Establishment of three-dimensional integrated "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for research of traditional Chinese medicine prescription and its application in Yinchenhao Tang / 中国中药杂志
Zhongguo Zhong Yao Za Zhi
; (24): 3786-3789, 2013.
Article
de Zh
| WPRIM
| ID: wpr-291283
Bibliothèque responsable:
WPRO
ABSTRACT
Traditional Chinese medicine (TCM) prescription is a valuable asset for clinical medication, has multi-component and multi-target characteristics. However, due to the complex ingredients of prescription, the unclear mechanism, the lack of scientific data to support the dose-response relationship, it has become the bottleneck for the in-depth study for the process of modernization and internationalization of TCM. It requires the integration of Chinese medicine theory, modern analysis and data mining technology to build new research model for characteristic of TCM prescription. This paper provides an overview of TCM serum pharmacochemistry, pharmacokinetics (pharmacodynamics) and systems biology theory and practice, to establish the integrated three-dimensional "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for the research of TCM prescription to reveal the pharma-material basis and action mechanism and the compatibility scientific connotation, with a prescription Yinchenhao Tang as a case study.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Ordonnances médicamenteuses
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Contrôle de qualité
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Normes de référence
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Médicaments issus de plantes chinoises
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Pharmacocinétique
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Chimie
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Sérum
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Biologie des systèmes
Type d'étude:
Prognostic_studies
Limites du sujet:
Animals
/
Humans
langue:
Zh
Texte intégral:
Zhongguo Zhong Yao Za Zhi
Année:
2013
Type:
Article