Extracorporeal Life Support in Patients with Hematologic Malignancies: A Single Center Experience
The Korean Journal of Thoracic and Cardiovascular Surgery
; : 280-286, 2016.
Article
de En
| WPRIM
| ID: wpr-29182
Bibliothèque responsable:
WPRO
ABSTRACT
BACKGROUND: Extracorporeal life support (ECLS) in patients with hematologic malignancies is considered to have a poor prognosis. However, to date, there is only one case series reported in the literature. In this study, we compared the in-hospital survival of ECLS in patients with and without hematologic malignancies. METHODS: We reviewed a total of 66 patients who underwent ECLS for treatment of acute respiratory failure from January 2012 to December 2014. Of these patients, 22 (32%) were diagnosed with hematologic malignancies, and 13 (59%) underwent stem cell transplantation before ECLS. RESULTS: The in-hospital survival rate of patients with hematologic malignancies was 5% (1/22), while that of patients without malignancies was 26% (12/46). The number of platelet transfusions was significantly higher in patients with hematologic malignancies (9.69±7.55 vs. 3.12±3.42 units/day). Multivariate analysis showed that the presence of hematologic malignancies was a significant negative predictor of survival to discharge (odds ratio, 0.07; 95% confidence interval, 0.01–0.79); p=0.031). CONCLUSION: ECLS in patients with hematologic malignancies had a lower in-hospital survival rate, compared to patients without hematologic malignancies.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pronostic
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Insuffisance respiratoire
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Oxygénation extracorporelle sur oxygénateur à membrane
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Analyse multifactorielle
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Taux de survie
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Transfusion de plaquettes
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Tumeurs hématologiques
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Transplantation de cellules souches
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Hématologie
Type d'étude:
Prognostic_studies
Limites du sujet:
Humans
langue:
En
Texte intégral:
The Korean Journal of Thoracic and Cardiovascular Surgery
Année:
2016
Type:
Article