Study on the production condition of extraction in combination hydrolysis in situ for isolating diosgenin / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the production technology of extraction in combination hydrolysis in situ for isolating diosgenin from Dioscorea nipponica by orthogonal design.</p><p><b>METHOD</b>The optimum production conditions were investigated with the recovery of diosgenin as an index by extraction in combination hydrolysis in situ, and were compared with the traditional method.</p><p><b>RESULT</b>Extraction in combination hydrolysis in situ conducted in 1.5 mol x L(-1) sulfuric acid of water containing 75% isopropanol at 100 degrees C for 4.5 h could get higher recovery of diosgenin than traditional methods.</p><p><b>CONCLUSION</b>This production technology can get higher recovery of diosgenin, and it is simple, time and money saving.</p>