Advances in study of dioscin--a natural product / 中国中药杂志
Zhongguo Zhong Yao Za Zhi
; (24): 36-41, 2015.
Article
de Zh
| WPRIM
| ID: wpr-305353
Bibliothèque responsable:
WPRO
ABSTRACT
Dioscin, a typical saponin, is widely present in the family of Dioscoreaceae, Liliaceae, Caryophyllaceae and Rosaceae, especially in Dioscoreaceae, including Discorea nipponica Makino, Dioscorea zingiberensis C. H. Wright and Dioscorea panthaica Prain et Burkill. Traditional Chinese medicine reported that dioscin plays a role in expectorant, relaxing the muscles and stimulating the blood circulation, aiding digestion and diuresis. With the development of science and technology in recent years, some new extraction and separation techniques and methods have been applied to the study of dioscin, and more and more pharmacological effects were found. Modern pharmacology studies have confirmed that dioscin had some activities on desensitization, anti-inflammatory, lipid-lowering, anti-tumor, hepatoprotection and anti-viral. After oral administration, dioscin is metabolized to diosgenin, which is the true active ingredient and is an important raw material to synthesize steroid hormone drugs. Therefore, the studies on dioscin are valueable and promising. In this review, we make a summary on the researches of dioscin including the extraction technology, separation and prepara- tion, chemical synthesis, drug metabolism, determination and pharmacological researches.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pharmacologie
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Produits biologiques
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Extraits de plantes
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Chimie
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Diosgénine
Limites du sujet:
Animals
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Humans
langue:
Zh
Texte intégral:
Zhongguo Zhong Yao Za Zhi
Année:
2015
Type:
Article