The Adverse Effect of the 2-1-1 Regimen for Rabies PEP in Preschool Children / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
; (12): 373-375, 2017.
Article
de En
| WPRIM
| ID: wpr-311403
Bibliothèque responsable:
WPRO
ABSTRACT
Post-exposure prophylaxis (PEP) has proved to be the most important measure for rabies prevention and control. There is little information regarding adverse reactions to the Essen and 2-1-1 regimens in preschool children (aged 0-6). We reexamined the outcomes of 1,109 preschool children who were vaccinated using SPEEDA under the Essen regimen between January 2011 and December 2012 and 1,267 preschool children under the 2-1-1 regimen between January 2013 and December 2014. We find that, in preschool children, the febrile reaction after the first 2-dose injection in the 2-1-1 regimen was significantly higher than that induced by the first 1-dose in the Essen procedure. Thus, we recommend that the Essen regimen should still be used for rabies PEP in preschool children.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Rage (maladie)
/
Normes de référence
/
Vaccins antirabiques
/
Vaccination
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Prophylaxie après exposition
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Allemagne
Limites du sujet:
Child
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Child, preschool
/
Humans
/
Infant
Pays comme sujet:
Europa
langue:
En
Texte intégral:
Biomedical and Environmental Sciences
Année:
2017
Type:
Article