Chemical constituents from Artemisia annua / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4816-4821, 2014.
Article
de Zh
| WPRIM
| ID: wpr-341810
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the chemical constituents of dried whole plants of Artemisia annua.</p><p><b>METHOD</b>The chemical constituents were isolated by repeated silica gel chromatography, medium pressure column chromatography, and semi-preparative HPLC, and their structures were elucidated by spectroscopic analyses and comparison of NMR data with those reported in literature.</p><p><b>RESULT</b>15 compounds were isolated and identified to be 5-O-[(E)-Caffeoyl] quinic acid(l), 1,3-di-O-caffeoylquinic acid(2), 4 5-di-O-caffeoylquinic acid(3), 3, 5-di-O-caffeoylquinic acid (4), 3, 4-di-O-caffeoylquinic acid (5), methyl-3,4-di-O-caffeoylquinic acid(6), methyl-3,5-di-O-caffeoylquinic acid(7), 3,6'-O-diferuloylsucrose(8), 5'-β-D-glucopyranosyloxyjasmonic acid(9), Scopoletin(10), scoparone (11), 4-O-β-D-glucopyranosyl-2-hydroxyl-6-methoxyacetophenone (12), chrysosplenol D (13), casticin (14), chrysosplenetin(15).</p><p><b>CONCLUSION</b>Compounds 2, 6, 8 and 9 are obtained from the Artemisia genus for the first time. Compounds 7 and 15 are obtained from this plant for the first time.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Plantes médicinales
/
Acide quinique
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Flavonoïdes
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Médicaments issus de plantes chinoises
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Chimie
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Chromatographie sur gel
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Chromatographie en phase liquide à haute performance
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Artemisia annua
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Gel de silice
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Médecine traditionnelle chinoise
Type d'étude:
Diagnostic_studies
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2014
Type:
Article