Clinical analysis of proteinuria and glomerular lesions in Henoch-Schönlein purpura nephritis of adults / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To analyze the characteristics of proteinuria and glomerular lesions in Henoch-Schönlein purpura nephritis (HSPN) of adults.</p><p><b>METHODS</b>The pathologic results and clinical data of 103 HSPN patients were analyzed.</p><p><b>RESULTS</b>Patients with mild or moderate proteinuria accounted for 40.8% and 37.9%, respectively. Patients with nephropathic proteinuria accounted for about 21.4%. Severer proteinuria resulted in higher blood pressure and increased cholesterol, and albumin decreased gradually (P < 0.01); meanwhile, total glomerular lesion, tubulointerstitial lesion, and vascular lesion also became severer (P < 0.01).</p><p><b>CONCLUSION</b>Proteinuria may indirectly reflect the severity of glomerular lesions in HSPN of adults.</p>