Rifampicin-Induced Minimal Change Disease Is Improved after Cessation of Rifampicin without Steroid Therapy
Yonsei Medical Journal
; : 582-585, 2015.
Article
Dans En
| WPRIM
| ID: wpr-38890
Responsable en Bibliothèque :
WPRO
ABSTRACT
There are several reports to demonstrate that rifampicin, a major anti-tuberculosis agent, is associated with some adverse renal effects, with a few cases of rifampicin-induced minimal change disease (MCD). In the present case, a 68-year-old female presented with nausea, vomiting, foamy urine, general weakness and edema. She had been taking rifampicin for 4 weeks due to pleural tuberculosis. The patient had no proteinuria before the anti-tuberculosis agents were started, but urine tests upon admission showed heavy proteinuria with a 24-h urinary protein of 9.2 g/day, and serum creatinine, albumin, and total cholesterol levels were 1.36 mg/dL, 2.40 g/dL, and 283 mg/dL, respectively. MCD was diagnosed, and the patient achieved complete remission after cessation of rifampicin without undergoing steroid therapy.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Protéinurie
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Rifampicine
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Tuberculose pleurale
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Induction de rémission
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Résultat thérapeutique
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Oedème
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Tests de la fonction rénale
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Glomérule rénal
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Antibiotiques antituberculeux
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Nausée
Limites du sujet:
Aged
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Female
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Humans
langue:
En
Texte intégral:
Yonsei Medical Journal
Année:
2015
Type:
Article