Clinical and pathological characteristics of IgA nephrology secondary to primary Sj(o)gren's syndrome / 中华风湿病学杂志
Chinese Journal of Rheumatology
; (12): 329-331, 2010.
Article
de Zh
| WPRIM
| ID: wpr-389774
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WPRO
ABSTRACT
Objective To analyze the clinical and pathologieal characteristics of IgA nephmlogy secondary to primary sj(o)gren's syndrome(pSS).Method The clinical and pathological data of 8 patients with pSS and IgA in Changzheng Hospital from 2004 to 2009 were analyzed.Results The average age of seven female and one male was (44±8) years old.Five patients presented with edema and proteinuria.Eight patients presented with microhematuria.The average 24-hour proteinuria was (3±4) g.Two patients had hypertension.Serum creatinine levels of two patients were higher than normal level,the others'were normal.Light microscopy examination showed three patients were mild mesangial proliferation with Lee's classification grade Ⅰ;five patients had global sclerosis with Lee's classification grade Ⅱ,Ⅲ and Ⅳ.Positive IgA was mainly found under immunofluorescence microscopy.Electronic microscopy showed no electron-dense deposits.Conclusion IgA nephrology secondary to pSS is different from primary IgA nephrology under immunofluorescence microscopy.
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Rheumatology
Année:
2010
Type:
Article