Research advances of phosphokinases for α-synuclein / 中国药理学与毒理学杂志
Chinese Journal of Pharmacology and Toxicology
; (6): 485-489, 2009.
Article
de Zh
| WPRIM
| ID: wpr-403781
Bibliothèque responsable:
WPRO
ABSTRACT
Abnormal aggregation of α-synuclein(α-Syn) is thought to be a key event in the pathogenesis of Parkinson disease (PD). In recent years, it was shown that above 90% of α-Syn deposited in Lewy bodies in brain tissues from patients with PD is phosphorylated, which suggested that α-Syn phosphorylation be connected with the occurrence of PD. Several kinds of phosphokinases can make α-Syn phosphorylated, however the precise roles of these phosphokinases in PD are less clear.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Pharmacology and Toxicology
Année:
2009
Type:
Article