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Association between the level of serum vitamin D and peripheral neuropathy in type 2 diabetic patients / 中华内分泌代谢杂志
Article de Zh | WPRIM | ID: wpr-446990
Bibliothèque responsable: WPRO
ABSTRACT
Objective To evaluate the relationship between 25-(OH) vitamin D [25-(OH) D] level and peripheral neuropathy in patients with type 2 diabetes mellitus.Methods Eighty patients with type 2 diabetes mellitus were enrolled in this cross-sectional study,including 37 subjects with and 43 without diabetic neuropathy.Anthropometric data was collected and serum levels of 25-(OH) D,HbA1c,blood lipid,and hepatic and renal functions were determined in all patients.Results Serum 25-(OH) D level was significantly lower in patients with diabetic neuropathy compared to those without neuropathy [(12.73 ± 4.68 vs 17.56 ± 5.28) ng/ml,P<0.01].Logistic regressions demonstrated that vitamin D level was associated with diabetic neuropathy (OR=1.222,95% CI 1.095-1.364).Conclusions Vitamin D insufficiency is associated with diabetic peripheral neuropathy.25-(OH) D level seems to be an independent risk factor of diabetic neuropathy in patients with type 2 diabetes mellitus.
Mots clés
Texte intégral: 1 Indice: WPRIM Type d'étude: Observational_studies / Risk_factors_studies langue: Zh Texte intégral: Chinese Journal of Endocrinology and Metabolism Année: 2014 Type: Article
Texte intégral: 1 Indice: WPRIM Type d'étude: Observational_studies / Risk_factors_studies langue: Zh Texte intégral: Chinese Journal of Endocrinology and Metabolism Année: 2014 Type: Article