The changes of Th17 and Th22 cells in patients with Helicobacter pylori infection / 国际检验医学杂志
International Journal of Laboratory Medicine
; (12): 2901-2902, 2014.
Article
de Zh
| WPRIM
| ID: wpr-460128
Bibliothèque responsable:
WPRO
ABSTRACT
Objective To investigate the changes of Th17 and Th22 cells in patients with Helicobacter pylori(HP)infection . Methods 66 cases of HP infection (HP infection group) and 30 cases of healthy people (control group) were selected .The levels of Th17 and Th22 cells in peripheral blood were measured by flow cytometry and the level of IL-17 and IL-22 in serum were meas-ured by ELISA .Results Comparing with the control group ,the levels of Th17 ,Th22 ,IL-17 and IL-22 were significantly increased in HP infection group(P<0 .05) .The correlation analysis showed that the levels of Th17 ,Th22 ,IL-17 and IL-22 were significantly positive correlated with DPM(P<0 .01) .Conclusion Th17 and Th22 cells were actived in patients with HP infection ,which caused the high expression of immune effector molecules ,and promoted the progress of immune damage .
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
International Journal of Laboratory Medicine
Année:
2014
Type:
Article