Radiotherapy sensitization mechanisms of tumor necrosis factor-α / 国际肿瘤学杂志

ABSTRACT

Tumor necrosis factor-α (TNF-α)is a kind of cytokines with a wide range of biological activity,which is closely related to the occurrence and development of various diseases.Nowadays,a number of researchers use TNF-α as a radiation-sensitizing agent to evaluate the effect of radiation sensitivity of tumor cells.The scheme may have correlation with cell apoptosis,cell cycle,hypoxic cells,repair of DNA damage,etc.