Effectiveness of Positron Emission Tomography in the Pre-operative Staging of Gastric Cancer
Journal of the Korean Gastric Cancer Association
; : 110-116, 2009.
Article
Dans Ko
| WPRIM
| ID: wpr-46553
Responsable en Bibliothèque :
WPRO
ABSTRACT
PURPOSE:
The aim of this study was to examine the usefulness of positron emission tomography (PET)-computed tomography (CT) in the pre-operative staging of gastric cancer. MATERIALS ANDMETHODS:
Between February 2006 and August 2008, PET-CT and CT were performed on 70 patients diagnosed with gastric cancer by gastrofiberscopic biopsy. The sensitivities, specificities, positive predictive value (PPV), and negative predictive value (NPV) of PET-CT and CT imaging for the detection of gastric cancer TNM staging were compared.RESULTS:
The detection rates for the primary tumor were as follows PET-CT, 81.4% (57/70); and CT, 42.9% (30/70). For both early gastric cancer (EGC) and advanced gastric cancer (AGC), PET-CT was more accurate than CT in detecting the lesions. As the size of the tumor exceeded 3 cm, the detection rate increased. The sensitivities, specificities, PPV, and NPV of PET-CT for lymph node staging were 55.6%, 81%, 86.2%, and 45.9%, while the sensitivities, specificities, PPV, and NPV of CT were 40.0%, 85.7%, 85.7% and 40%, respectively. One case of multiple liver metastasis and two cases of dual primary cancer (rectal and pancreatic cancers) were detected by PET-CT. PET-CT also had a higher detection rate for all histologic types of primary tumors. PET-CT was more accurate than CT in detecting primary gastric cancer lesions. The detection of nodal metastasis by PET-CT was similar to CT; small-sized tumors or EGC detection rates were not high. However, PET-CT provided additional information to detect distant metastases and dual primary cancers and reduced unnecessary laparotomies to detect peritoneal seeding or carcinomatosis.CONCLUSION:
It would be useful to make a pre-operative diagnosis of gastric cancer and determine treatment if PET-CT were added to other routine pre-operative studies.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Graines
/
Tumeurs de l'estomac
/
Biopsie
/
Tomographie par émission de positons
/
Électrons
/
Laparotomie
/
Foie
/
Noeuds lymphatiques
/
Métastase tumorale
/
Stadification tumorale
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Journal of the Korean Gastric Cancer Association
Année:
2009
Type:
Article