Treatment of Herpes Zoster with Recombinant Interferon (IFN alfa-1b) Cream: A Randomized, Double-blind, Placebo-controlled, Multi-center Clinical Trial / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12)2003.
Article
Dans Zh
| WPRIM
| ID: wpr-522874
Responsable en Bibliothèque :
WPRO
ABSTRACT
Objective To observe the clinical efficacy and safety of topical interferon alfa-1b cream in the treatment of herpes zoster. Methods A randomized, double-blind, parallel placebo-controlled clinical study was conducted. The test drug was topically used in herpes zoster patients, three times a day for 2 weeks. Patients whose skin lesions cleared completely were followed for 29 days to observe postherpetic neuralgia. Results One hundred and twenty-eight patients with herpes zoster were enrolled into this trial. Sixty-five patients were randomly selected to receive interferon alfa-1b cream and sixty-three patients received vehicle cream. After following up for 11, 14, 22, 29 days the cure rates were 69.2%, 81.5%, 90.8%, 95.4% respectively in the study group and were 57.1%, 71.4%, 84.1% and 84.1% respectively in the control group(P
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Clinical_trials
langue:
Zh
Texte intégral:
Chinese Journal of Dermatology
Année:
2003
Type:
Article