Experiment research of anti-PG cell metastasis and mechanism of a new Chinese herb Qcimum basilicum polysaccharide / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12)2000.
Article
Dans Zh
| WPRIM
| ID: wpr-525361
Responsable en Bibliothèque :
WPRO
ABSTRACT
AIM:
In this paper, we studied the efficiencies and the mechanisms of a new Chinese herb Qcimum basilicum polysaccharide (BP) on PG cell metastasis in vitro.METHODS:
The number of tumor cells going through matrigel was assayed and used to represent the ability of the invasion and migration of PG cells. Using Scrape-loading and dye transfer (SLDT) technique, the efficiencies of BP on recovering PG cell gap junction -mediated intercellular communication (GJIC) was measured. The expressions of c-myc, nm23-H1 and Tiam-1 genes mRNA in PG cells treated with BP were determined by RT-PCR.RESULTS:
Compared with the control, the action of invasion and migration of PG cells were decreased after treated with BP (P
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Pathophysiology
Année:
2000
Type:
Article