A Short-time Clinical Study on the Efficacy of Homemade Sterilized Powder for Injection of Rifampicin in the Treatment of Pulmonary Tuberculosis / 中国药房
China Pharmacy
; (12)2005.
Article
Dans Zh
| WPRIM
| ID: wpr-528467
Responsable en Bibliothèque :
WPRO
ABSTRACT
OBJECTIVE:
To study and evaluate the efficacy and safety of homemade sterilized powder for injection of rifampicin(weifunin) in the treatment of pulmonary tuberculosis(PT) and to compared with same import preparation .METHODS:
Divide the 121 of bacteriological positive PT patients in the proportion of 1 to 1 with computer automatically into the trial group and the control group used with homemade rifampicin (weifuxin) and import rifampicin(nifu)respectively,the others regimens was same in 2 groups,to evaluate the sputum culture negative conversion rates,X-ray results and adverse drug event etc.after treatment 1 and 2 months .RESULTS:
116 cases were finished ,at the end of 2 month the sputum smear negative conversion rates were 86.21 % and 91.38% (X2=0.780,P=0.377), the sputum culture negative conversion rates were 91.38% and 93.10%(X2=0.120,P=0.729)in the trial group and the control group respectively .The X-ray remarkable effective rates of 2 groups were 82.76% amd 70.69%(X2=2.365,P=0.124)respectively, and the effective rates of the 2 groups were both be 96.55% .The adverse drug event rates were 8.20% and 11.67% respectively, there was on sighificant difference in each indexes .CONCLUSIONS:
2 preparation were similar in efficacy ,safety and tolerance.
Texte intégral:
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Indice:
WPRIM
langue:
Zh
Texte intégral:
China Pharmacy
Année:
2005
Type:
Article