Quality Standard of Danqitong Tablets / 中国药房

ABSTRACT

OBJECTIVE:To establish the quality standard of Danqitong tablets.METHODS:Salvia miltiorrhiza and Ra-dix Astragali in the formulation were identified qualitatively by TLC,and the contents of total saponins and tanshinone-Ⅱ A in the tablets were determined by visible ultraviolet spectrophotometry and HPLC,respectively.RESULTS:The TLC spots of Salvia miltiorrhiza and Radix Astragali were clear and well-separated.The linear ranges of total saponins and tanshinone-Ⅱ A were 0.056～0.12 mg?mL-1(r=0.999 3)and 0.002 019～0.032 13 mg?mL-1(r=0.999 9),respectively,and the average recovery rates were 97.61%(RSD=2.10%)and 95.74%(RSD=1.93%),respectively.CONCLUSION:The established standard is applicable for the quality control of Danqitong tablets.