The clinical significance of lowering the cut-point of impaired fasting glucose:in view of cardiovascular risk factors / 中华内分泌代谢杂志

ABSTRACT

Objective To evaluate the rationale of lowering the cutoff value of normal fasting plasma glucose (FPG) by studying the cardiovascular risk factors in subjects with different FPG levels and different glucose tolerance states. Methods A population-based survey of diabetes was undertaken in 1994, data from 15564 Chinese adults (age≥25) who adopted 75 g-oral glucose tolerance test were analyzed. Results (1) The frequencies of BMI≥25 kg/m 2 , hypertension, hypertriglyceridemia, metabolic syndrome were increasing with graded FPG levels at a 0.56 mmol/L interval. FPG at 5.0-5.6 mmol/L level overweight frequency elevated significantly (P=0.001), and FPG at 5.6-6.1 mmol/L level the metabolic syndrome and other components also elevated (P