Effects of TGF-?1 on production of a-SMA and extracellular matrix in flexor tendon sheath fibroblasts / 中国矫形外科杂志
Orthopedic Journal of China
; (24)2006.
Article
de Zh
| WPRIM
| ID: wpr-548642
Bibliothèque responsable:
WPRO
ABSTRACT
[Objective]To examine the effects of TGF-?1 on the production of ?-SMA and extracellular matrix in flexor tendon sheath fibroblasts. [Methods]Sheath fibroblasts were obtained from rabbit flexor tendons.Cell culture was supplemented with 5ng/ml of TGF-?1.After 48 hours incubation,the production of a-SMA was assayed by Western-Blot.The productions of collagen I and fibronectin in supernatants culture were examined using ELISA.[Results]Treatment with TGF-?1 significantly stimulated a-SMA production in flexor tendon sheath fibroblasts (P
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Orthopedic Journal of China
Année:
2006
Type:
Article