Antiarrhythmic effects of 13 - n - Propyl-Palmatine / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1986.
Article
de Zh
| WPRIM
| ID: wpr-550969
Bibliothèque responsable:
WPRO
ABSTRACT
Intravenous injection of 13-n-Propyl-Palmatine 8 mg ? kg-1 reduced markedly the incidence of VF induced by chlorofom in the mice,elevated the threshold doses of Ouabain induced VP,VT,VF,CA in guinea pigs. Iv 1, 3mg ? kg-1 reduced signifi- cantly the incidence of arrhythmia induced by CaCl2 in the mice,shortened the total duration of arrhythmia induced by BaCl3 in therats. However, it was not so effective on A-conitine - induced arrhythmia in the rats. In addition, 13 - n - Propyl - Palmatine elevated significantly the activities of Na+, K+ - AT-Pase in the myocardial cellular membranes of rats.
Texte intégral:
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Pharmacological Bulletin
Année:
1986
Type:
Article