Comparison of the bronchodilation curve in patients with COPD or asthma / 中国实用内科杂志

ABSTRACT

Objective To set up bronchodilation curve in patients with chronic obstructive pulmonary disease(COPD)or asthma and investigate the features of large and small airways dilation.Methods Pulmonary functions of 44 COPD and 68 asthma patients were determined before and after inhaling Formoterol.Results The curves of FEV1 and FVC rose at 15 minutes after inhaling Formoterol and then declined at 120 minutes post-formoterol in patients with COPD.The curves of FEV1/FVC and FEF75 presented as a wave form,and the curves of FEF50 and FEF75/25 rose at 30 minutes and declined after 30 minutes.The fitting quadr-curves model equations for FEV1,FVC and FEF50 over time were statistically significant(P