Impaired Diastolic Recovery after Acute Myocardial Infarction as a Predictor of Adverse Events
Journal of Cardiovascular Ultrasound
; : 150-157, 2015.
Article
Dans En
| WPRIM
| ID: wpr-58495
Responsable en Bibliothèque :
WPRO
ABSTRACT
BACKGROUND:
To investigate the impact of left ventricular (LV) diastolic functional recovery on major adverse cardiac events (MACE) 6 months after acute myocardial infarction (AMI) in patients with preserved LV systolic function.METHODS:
A total 463 patients with preserved LV systolic function at 6 months after an AMI were divided into two groups based on the extent of diastolic recovery assessed by echocardiography group I (n = 241) showed improving diastolic function and group II (n = 222) did not. MACE included death, recurrent myocardial infarction, and rehospitalization due to heart failure, and these events were compared with the patients' characteristics at baseline.RESULTS:
Compared with group I, the patients in group II were older and had a higher prevalence of hypertension and diabetes. Blood levels of hemoglobin and triglyceride were lower in group II, whereas the levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and of high-sensitivity C-reactive protein were higher in this group than in group I. MACE were significantly more frequent in group II than in group I. Age, elevated NT-proBNP, and impaired diastolic recovery were significant independent predictors of MACE.CONCLUSION:
Despite improvement in LV systolic function, LV diastolic function had not improved in 222 patients (47.9%) by the 6-month follow-up after the index AMI, and impaired diastolic functional recovery was found to be an independent predictor of MACE. Evaluation of diastolic function would be a useful way to stratify risk in patients discharged after an index AMI.
Texte intégral:
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Indice:
WPRIM
Sujet Principal:
Pronostic
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Triglycéride
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Protéine C-réactive
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Échocardiographie
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Prévalence
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Études de suivi
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Défaillance cardiaque
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Hypertension artérielle
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Infarctus du myocarde
Type d'étude:
Observational_studies
/
Prevalence_studies
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Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Humans
langue:
En
Texte intégral:
Journal of Cardiovascular Ultrasound
Année:
2015
Type:
Article