Progress in ultrasonic diagnosis of thyroid cancer and related molecular marker detection / 国际生物医学工程杂志

ABSTRACT

With the development of ultrasonic imaging technique,the thyroid nodule detection rate is ever increasing.However,there is still no unique characteristic for the identification of benign and malignant lesions in ultrasonogram.On the basis of conventional ultrasound performance of nodules,thyroid imaging reporting and data system for the correct classification of thyroid nodules is conducive to their differential diagnosis.Contrast enhanced ultrasound (CEUS) can show the microvascular status of the lesion,and the benign and malignant thyroid nodules can be analyzed by observing the different enhancement patterns.By evaluating the difference in hardness between different tissues,the ultrasonic elastography (.UE) provides a complementary method for the identification of benign and malignant thyroid nodules.Ultrasound-guided fine-needle aspiration biopsy (US-FNAB) can accurately locate and offer pathological basis for preoperative diagnosis of thyroid nodules.It is helpful to preoperatively diagnose the thyroid cancer by detecting the molecular marker of the biopsy specimens which are difficult to be diagnosed clearly.