Expression Pattern of Immunoproteasome Subunits in Human Thymus
Immune Network
; : 285-288, 2009.
Article
Dans En
| WPRIM
| ID: wpr-60577
Responsable en Bibliothèque :
WPRO
ABSTRACT
The expression pattern of immunoproteasomes in human thymus has not been analyzed but may have important consequences during thymic selection. Here we examined the expression patterns of immunoproteasome subunits in fetal and adult thymic tissues by immunohistochemistry and found that all three subunits are expressed in both cortical and medullary stromal cells. These data suggest that thymic selection in human can be affected by peptide repertoires generated by immunoproteasomes.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Thymus (glande)
/
Immunohistochimie
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Cellules stromales
Limites du sujet:
Adult
/
Humans
langue:
En
Texte intégral:
Immune Network
Année:
2009
Type:
Article