The clinical efficacy of microwave ablation under CT-guidance for patients with liver cancer of the first hepatic hilar region at advanced period / 中国医学装备

ABSTRACT

Objective:To explore the clinical efficacy of microwave ablation under CT-guidance for patients with liver cancer of the first hepatic hilar region at advanced period.Methods: 56 patients with liver cancer of the first hepatic hilar region at advanced period, who had lost the chance of operative treatment, were divided into observation group (28cases) and control group (28cases) as the random number table. The patients of observation group received CT-guidance microwave ablation and other targeted combining therapy while patients of control group underwent routine chemotherapy of arterial embolism. The therapeutic effect and survival situation of the two groups were compared and analyzed.Results: The total effective rate of patients with liver cancer of the observation group(82.14%) was significantly higher than that of control group (46.43%)(x2=7.778,P<0.05). The AFP of both of the two group was obviously reduced, and the improvement degree of observation group was significantly better than that of control group (t=14.662,P<0.05). The survival rate of post-operative 1-2 y of observation group was slightly higher than that of control group, but it was no significant (x2=4.156,x2=0.080,P>0.05).During the process of treatment and post the process of treatment, the occurrence rate of adverse reaction of observation group was significantly lower than that of control group (x2=6.842,P<0.05).Conclusion: The microwave ablation under CT-guidance and other targeted combining therapy has outstanding advantages including simple operation, curative precision and so on. And it has better curative effect for patients with liver cancer of the first hepatic hilar region at advanced period who had lost optimum opportunity of operative treatment. Besides, its adverse reaction is lower and it has obviously preponderance to compare with routine arterial embolism.