Prevention of postpartum hemorrhage and diverticulum in scarred uterus with oxytocin and hemabate / 中国生化药物杂志

ABSTRACT

Objective To investigate the efficacy of oxytocin combined with hemabate in the prevention of postpartum hemorrhage and diverticulum in scarred uterus. Methods 88 patients with scar uterus, postpartum hemorrhage and diverticulum in Chang'an Hospital from May 2016 to May 2017 were divided into two groups by maternal numbering and randomization, with 44 patients in each group. The control group was treated with oxytocin, and the observation group was treated with oxytocin combined with hemabate. It must compare the amount of bleeding, the amount of 2 h bleeding, the amount of postpartum 24 h bleeding and the incidence of adverse reactions in the two groups after the treatment. Results Compared with the control group, the amount of bleeding, the amount of two hours' bleeding and the amount of postpartum 24 hours' bleeding in the observation group were significantly lower than that in the control group(P<0.05). The postpartum hemorrhage volume of the observation group was 6.81%, which was lower than that of the control group, and the rate of postpartum hemorrhage was 27.27% (P<0.05). The incidence of adverse reactions such as nausea, vomiting, heart rate and blood pressure in the observation group was significantly lower than that in the control group (4.54% vs. 18.18%), the difference was statistically significant(P<0.05). Conclusion In the scar uterus, postpartum hemorrhage and diverticulum, the use of oxytocin combined with hemabate treatment has obvious curative effect. It is an important measure to reduce the amount of bleeding and ensure safety.