Research progress of the cell microencapsulation / 国际生物医学工程杂志
International Journal of Biomedical Engineering
; (6): 291-294,301, 2017.
Article
Dans Zh
| WPRIM
| ID: wpr-662996
Responsable en Bibliothèque :
WPRO
ABSTRACT
Cell microencapsulation aims to wrap the living target cells by one or several materials with good biological compatibility and semipermeable membrane properties.Cell microencapsulation not only can achieve immune isolation and prevent the attacks by macromolecular immunes and immune cells,but also can allow the free access of metabolites,small molecule nutrients and bioactive substances to the microcapsule.With the continuous progress of interdisciplinary technologies,cell microencapsulation shows increasing application prospects of making up a variety of limitations of organ transplantation.Moreover,with the development and maturation of cell microencapsulation,it has shown a strong advantage in regenerative medicine,which will certainly promote the rapid development of artificial cells and artificial organs.In this paper,the preparation of cell microcapsules,the effects of the outer membrane of microcapsules on immunological macromolecules and cytokines,the immunogenicity of the outer membrane,and the representative applications of cell microencapsulation were summarized.
Texte intégral:
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Indice:
WPRIM
langue:
Zh
Texte intégral:
International Journal of Biomedical Engineering
Année:
2017
Type:
Article