Effects of Sanbaoxin on Formation of Thrombosis In Vivo and In Vitro in Rats / 中医杂志

ABSTRACT

Objective:To observe effects of Sanbaoxin on formation of thrombosis in vivo and in vitro in rats.Methods:After the rats were administrated by high,mid and low doses,i,e,10g crude drug/kg,5g/kg and 1g/kg,respectively,Chandler method was used to form in vitro thrombosis and electrical stimulation of common carotid artery was used to form in vivo thrombosis,and then effects of Sanbaoxin on formation of thrombosis were observed.Results:The high dosage of Sanbaoxin could significantly prolongate the period of in vivo thrombosis(P