Research progress in changes of intestinal flora in neonatal necrotizing enterocolitis / 中华实用儿科临床杂志

ABSTRACT

Neonatal necrotizing enterocolitis (NEC) is the most common neonatal gastrointestinal emergency,and its pathogenesis is still not clear.In recent years,intestinal flora has been keenly concerned about its pivotal role in the progress of NEC pathology.At the technical level,the popularity and in-depth development of high throughput sequencing,fluorescence in situ hybridization and polymerase chain reaction-denaturing gradient gel electrophoresis are also favorable conditions for further study of the correlation between NEC and intestinal flora.Now,the relationship between the pathological development of NEC and intestinal flora was reviewed.