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Bone Health in Adrenal Disorders
Article de En | WPRIM | ID: wpr-713217
Bibliothèque responsable: WPRO
ABSTRACT
Secondary osteoporosis resulting from specific clinical disorders may be potentially reversible, and thus continuous efforts to find and adequately treat the secondary causes of skeletal fragility are critical to ameliorate fracture risk and to avoid unnecessary treatment with anti-osteoporotic drugs. Among the hyperfunctional adrenal masses, Cushing's syndrome, pheochromocytoma, and primary aldosteronism are receiving particularly great attention due to their high morbidity and mortality mainly by increasing cardiovascular risk. Interestingly, there is accumulating experimental and clinical evidence that adrenal hormones may have direct detrimental effects on bone metabolism as well. Thus, the present review discusses the possibility of adrenal disorders, especially focusing on pheochromocytoma and primary aldosteronism, as secondary causes of osteoporosis.
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Texte intégral: 1 Indice: WPRIM Sujet Principal: Ostéoporose / Phéochromocytome / Mortalité / Syndrome de Cushing / Hyperaldostéronisme / Métabolisme Type d'étude: Prognostic_studies langue: En Texte intégral: Endocrinology and Metabolism Année: 2018 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Ostéoporose / Phéochromocytome / Mortalité / Syndrome de Cushing / Hyperaldostéronisme / Métabolisme Type d'étude: Prognostic_studies langue: En Texte intégral: Endocrinology and Metabolism Année: 2018 Type: Article