Analytical Performance of New ARCHITECT AFP Assay: Comparison with the Current Assay
Laboratory Medicine Online
; : 62-65, 2018.
Article
Dans En
| WPRIM
| ID: wpr-713886
Responsable en Bibliothèque :
WPRO
ABSTRACT
Alpha-fetoprotein (AFP) is frequently used for hepatocellular carcinoma (HCC) diagnosis and surveillance. Although the current ARCHITECT AFP (List number 7K67) assay range is 0–350 ng/mL, all samples with test results between 200 and 350 ng/mL must be diluted and retested until their levels are <200 ng/mL. A new ARCHITECT AFP (8100/3P36) assay with a dynamic range of up to 2000 ng/mL has been introduced. The aim of this study was to perform a method comparison between the current ARCHITECT AFP assay and the new assay. The precision study showed excellent results for both high and low controls. There was a positive correlation between the two assay systems and clinical samples. The new ARCHITECT AFP assay with a wide assay range demonstrated good analytical performance. Therefore, the current ARCHITECT AFP assay could be replaced by the new assay, which is more convenient and minimizes manual labor.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Alphafoetoprotéines
/
Carcinome hépatocellulaire
/
Diagnostic
/
Méthodes
Type d'étude:
Diagnostic_studies
/
Guideline
langue:
En
Texte intégral:
Laboratory Medicine Online
Année:
2018
Type:
Article