Diffusion-Weighted Imaging of Upper Abdominal Organs Acquired with Multiple B-Value Combinations: Value of Normalization Using Spleen as the Reference Organ
Korean Journal of Radiology
; : 389-396, 2018.
Article
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| WPRIM
| ID: wpr-715453
Responsable en Bibliothèque :
WPRO
ABSTRACT
OBJECTIVE:
To compare apparent diffusion coefficient (ADC) of the upper abdominal organs acquired with multiple b-value combinations and to investigate usefulness of normalization. MATERIALS ANDMETHODS:
We retrospectively analyzed data, including 3T diffusion-weighted images, of 100 patients (56 men, 44 women; mean age, 63.9) that underwent liver magnetic resonance imaging. An ADC map was derived with the following six b-value combinations b1 = 0, 50, 400, 800; b2 = 0, 800; b3 = 0, 50, 800; b4 = 0, 400, 800; b5 = 50, 800; and b6 = 50, 400, 800 s/mm2. ADC values of the right liver lobe, left liver lobe, spleen, pancreas, right kidney, and left kidney were measured. ADC values of the spleen were used for normalization. Intraclass correlation coefficients (ICCs), comparison of dependent ICCs, and repeated-measures analysis of variance were used for statistical analysis.RESULTS:
Intraclass correlation coefficients of the original ADC revealed moderate to substantial agreement (0.5145–0.6509), while normalized ADCs revealed almost perfect agreement (0.8014–0.8569). ICC of normalized ADC for all anatomical regions revealed significantly less variability than that of the original ADC (p < 0.05). Coefficient of variance for normalized ADC was significantly lower than that for the original ADC (3.0.3.8% vs. 4.8.8.8%, p < 0.05).CONCLUSION:
Normalization of the ADC values of the upper abdominal organs using the spleen as the reference organ significantly decreased variability in ADC measurement acquired with multiple b-value combinations.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pancréas
/
Rate
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Imagerie par résonance magnétique
/
Études rétrospectives
/
Diffusion
/
Rein
/
Foie
Type d'étude:
Observational_studies
Limites du sujet:
Female
/
Humans
/
Male
langue:
En
Texte intégral:
Korean Journal of Radiology
Année:
2018
Type:
Article