Successful treatment of disseminated interdigitating dendritic cell sarcoma with adriamycin, bleomycin, vinblastine, and dacarbazine chemotherapy
Korean Journal of Hematology
; : 150-153, 2012.
Article
de En
| WPRIM
| ID: wpr-720180
Bibliothèque responsable:
WPRO
ABSTRACT
Interdigitating dendritic cell sarcoma (IDCS) is a very rare and aggressive neoplasm that arises from antigen presenting cells. IDCS usually involves lymph nodes; however, extra-nodal involvement has also been reported. Because a consistent standard therapy for IDCS has not been established to date, we report a case of the successful treatment of disseminated IDCS using ABVD chemotherapy (doxorubicin, bleomycin, vinblastine, and dacarbazine). A 64-year-old man was diagnosed with IDCS on the basis of immunohistochemical findings of a biopsy specimen of the inferior nasal concha. Immunohistochemical staining showed a positive reaction for CD68, leukocyte common antigen, and S-100 protein, but a negative reaction for CD34, CD1a, and CD21. Imaging studies showed cervical and axillary lymphadenopathies, subcutaneous nodules, and a soft tissue lesion in the nasal cavity. Treatment with the ABVD regimen resulted in complete remission after 8 cycles of chemotherapy.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Cornets
/
Vinblastine
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Biopsie
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Bléomycine
/
Cellules dendritiques
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Protéines S100
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Antigènes CD45
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Dacarbazine
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Sarcome à cellules dendritiques interdigitées
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Cellules présentatrices d'antigène
Limites du sujet:
Humans
langue:
En
Texte intégral:
Korean Journal of Hematology
Année:
2012
Type:
Article