A Case of Pleural Involvement in Patient with Waldenstr m's Macroglobulinemia / 대한혈액학회지
Korean Journal of Hematology
; : 630-635, 1999.
Article
de Ko
| WPRIM
| ID: wpr-720668
Bibliothèque responsable:
WPRO
ABSTRACT
Waldenstr m's macroglobulinemia (WM) is a rare lymphoproliferative disorder characterized by lymphocytic tumor infiltration of the bone marrow and monoclonal IgM gammopathy. There had been anecdotal reports of pleural involvement in WM. We experienced a case of WM with pleural involvement and reported here for the first time in Korea with review of literature. A 73-year-old male patient was admitted to our hospital due to dizziness and general weakness. Serum protein electrophoresis showed M-peak in the gamma-globulin region, which was revealed as IgM kappa macroglobulin by serum and urine immunoelectrophoresis. He complained headache, visual disturbance and epistaxis associated with hyperviscosity syndrome and plasma filtration and combination chemotherapy was performed immediately. Symptoms and laboratory parameters such as serum IgM level and globulin fraction were markedly improved thereafter. But during the treatment, insidiously progressive exertional dyspnea was developed and the chest X-ray showed bilateral pleural effusion. The pleural fluid contained abundant plasmacytoid lymphocytes with reactive mesothelial cells. His dyspnea was completely resolved with clearing of the radiographic pleural effusion after continued steroid therapy.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Plasma sanguin
/
Épanchement pleural
/
Thorax
/
Moelle osseuse
/
Gammaglobulines
/
Immunoglobuline M
/
Immunoélectrophorèse
/
Lymphocytes
/
Épistaxis
/
Macroglobulinémie de Waldenström
Limites du sujet:
Aged
/
Humans
/
Male
Pays comme sujet:
Asia
langue:
Ko
Texte intégral:
Korean Journal of Hematology
Année:
1999
Type:
Article